-lesion greater than 5 mm
-atypical reticular pattern (some areas with broadened pigment network)
-globules (rares)
-hypopigmented areas
-structureless area
Extirpation was indicated. Histopathology correlation was: lentiginous junctional nevus
-multicomponent pattern
-irregular and broadned pigment network
-globules
-blotches
-hypopigmented and structureless area
-blue-white veil
-regression areas (scar-like depigmentation)
-erythema
-red lacunae on the left side of lesion (second dermascopic picture)
Excision was indicated and histology confirmed the diagnosis of melanoma in situ
Comments: the image of red lacunae might correspond to a cherry hemangioma (collision tumor).
a multicomponent pattern is observed:
-asymmetrical pigmentation pattern: eccentric hyperpigmentation (blotch)
-broadened pigment network
-globules
-irregular hypopigmentation
-target-like structures
Excision was indicated
Dermoscopy signs in favor of melanoma
Comments: Arevalo A et al observed that eccentric hyperpigmentation and multicomponent pattern are significant predictors of melanoma when other melanoma features are present.
For more information: Arevalo A et al. The significance of eccentric and central hyperpigmentation, multifocal hyper/hypopigmentation, and the multicomponent pattern in melanocytic lesions lacking specific dermoscopic features of melanoma. 2008. Arch Dermatol 144: 1440-1444